Gunzner, Janet L.: search on Z-Library

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1

The Wittig and Related Reactions in Natural Product Synthesis

K. C. Nicolaou, Michael W. Härter, Janet L. Gunzner, Alan Nadin

Journal:

European Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 2.16 MB

english, 1997

2

10.1038/32623

Nicolaou, K. C., Yang, Zhen, Shi, Guo-qiang, Gunzner, Janet L., Agrios, Konstantinos A., Gärtner, Peter

Journal:

Year:

1998

Language:

english

File:

PDF, 352 KB

english, 1998

3

Total Synthesis of Brevetoxin A: Part 1: First Generation Strategy and Construction of BCD Ring System

K. C. Nicolaou, Mark E. Bunnage, Daniel G. McGarry, Shuhao Shi, Patricia K. Somers, Paul A. Wallace, Xin-Jie Chu, Konstantinos A. Agrios, Janet L. Gunzner, Zhen Yang

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 470 KB

english, 1999

4

Total Synthesis of Brevetoxin A: Part 2: Second Generation Strategy and Construction of EFGH Model System

K. C. Nicolaou, Paul A. Wallace, Shuhao Shi, Michael A. Ouellette, Mark E. Bunnage, Janet L. Gunzner, Konstantinos A. Agrios, Guo-qiang Shi, Peter Gärtner, Zhen Yang

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 252 KB

english, 1999

5

Callipeltoside A: Assignment of Absolute and Relative Configuration by Total Synthesis

Barry M. Trost, Olivier Dirat, Janet L. Gunzner

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 78 KB

english, 2002

6

An unusual regioselectivity in the Pd-catalyzed cross coupling of alkynes. A correction

Barry M Trost, Janet L Gunzner, Tatsuro Yasukata

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

7

Fragment-Based Identification of Amides Derived from trans -2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT)

Giannetti, Anthony M., Zheng, Xiaozhang, Skelton, Nicholas J., Wang, Weiru, Bravo, Brandon J., Bair, Kenneth W., Baumeister, Timm, Cheng, Eric, Crocker, Lisa, Feng, Yezhen, Gunzner-Toste, Janet, Ho, Y

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.96 MB

english, 2014

8

Total Synthesis of Brevetoxin A: Part 3: Construction of GHIJ and BCDE Ring Systems

K. C. Nicolaou, Guo-qiang Shi, Janet L. Gunzner, Peter Gärtner, Paul A. Wallace, Michael A. Ouellette, Shuhao Shi, Mark E. Bunnage, Konstantinos A. Agrios, Chris A. Veale, Chan-Kou Hwang, John Hutchin

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 407 KB

english, 1999

9

Total Synthesis of Brevetoxin A: Part 4: Final Stages and Completion

K. C. Nicolaou, Janet L. Gunzner, Guo-qiang Shi, Konstantinos A. Agrios, Peter Gärtner, Zhen Yang

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 318 KB

english, 1999

10

Potent and Selective Aminopyrimidine-Based B-Raf Inhibitors with Favorable Physicochemical and Pharmacokinetic Properties

Mathieu, Simon, Gradl, Stefan N., Ren, Li, Wen, Zhaoyang, Aliagas, Ignacio, Gunzner-Toste, Janet, Lee, Wendy, Pulk, Rebecca, Zhao, Guiling, Alicke, Bruno, Boggs, Jason W., Buckmelter, Alex J., Choo, E

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 4.52 MB

english, 2012

11

Identification and synthesis of [1,2,4]triazolo[3,4-a]phthalazine derivatives as high-affinity ligands to the α2δ-1 subunit of voltage gated calcium channel

Alec D. Lebsack, Janet Gunzner, Bowei Wang, Richard Pracitto, Hervé Schaffhauser, Angelina Santini, Jayashree Aiyar, Robert Bezverkov, Benito Munoz, Wensheng Liu, Shankar Venkatraman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 289 KB

english, 2004

12

Corrigendum to “GDC-0449—A potent inhibitor of the hedgehog pathway” [Bioorg. Med. Chem. Lett. 19 (2009) 5576]

Kirk D. Robarge, Shirley A. Brunton, Georgette M. Castanedo, Yong Cui, Michael S. Dina, Richard Goldsmith, Stephen E. Gould, Oivin Guichert, Janet L. Gunzner, Jason Halladay, Wei Jia, Cyrus Khojasteh,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 109 KB

english, 2010

13

Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor

Timothy P. Heffron, Megan Berry, Georgette Castanedo, Christine Chang, Irina Chuckowree, Jennafer Dotson, Adrian Folkes, Janet Gunzner, John D. Lesnick, Cristina Lewis, Simon Mathieu, Jim Nonomiya, Al

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1001 KB

english, 2010

14

ChemInform Abstract: An Unusual Regioselectivity in the Pd-Catalyzed Cross Coupling of Alkynes. A Correction.

Barry M. Trost, Janet L. Gunzner, Tatsuro Yasukata

Journal:

Year:

2001

File:

PDF, 33 KB

2001

15

Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties

Gunzner-Toste, Janet, Zhao, Guiling, Bauer, Paul, Baumeister, Timm, Buckmelter, Alexandre J., Caligiuri, Maureen, Clodfelter, Karl H., Fu, Bang, Han, Bingsong, Ho, Yen-Ching, Kley, Nikolai, Liang, Xia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 3.58 MB

english, 2013

16

Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer

Sutherlin, Daniel P., Bao, Linda, Berry, Megan, Castanedo, Georgette, Chuckowree, Irina, Dotson, Jenna, Folks, Adrian, Friedman, Lori, Goldsmith, Richard, Gunzner, Janet, Heffron, Timothy, Lesnick, Jo

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 3.50 MB

english, 2011

17

GDC-0449—A potent inhibitor of the hedgehog pathway

Kirk D. Robarge, Shirley A. Brunton, Georgette M. Castanedo, Yong Cui, Michael S. Dina, Richard Goldsmith, Stephen E. Gould, Oivin Guichert, Janet L. Gunzner, Jason Halladay, Wei Jia, Cyrus Khojasteh,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 2.02 MB

english, 2009

18

ChemInform Abstract: Total Synthesis of Deschlorocallipeltoside A.

Barry M. Trost, Janet L. Gunzner

Journal:

Year:

2002

File:

PDF, 25 KB

2002

19

Copper(I)-Promoted Stille Cross-Coupling of Stannyl Enol Ethers with Enol Triflates: Construction of Complex Polyether Frameworks

Prof. Dr. K. C. Nicolaou, Mitsunobu Sato, Dr. Neil D. Miller, Janet L. Gunzner, Dr. Johanne Renaud, Dr. Edouard Untersteller

Journal:

Angewandte Chemie International Edition

Year:

1996

Language:

english

File:

PDF, 300 KB

english, 1996

20

Second generation 2-pyridyl biphenyl amide inhibitors of the hedgehog pathway

Georgette M. Castanedo, Shumei Wang, Kirk D. Robarge, Elizabeth Blackwood, Daniel Burdick, Christine Chang, Gerrit J.P. Dijkgraaf, Stephen Gould, Janet Gunzner, Oivin Guichert, Jason Halladay, Cyrus K

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 455 KB

english, 2010

21

ChemInform Abstract: Total Synthesis of Brevetoxin A. Part 1. First Generation Strategy and Construction of BCD Ring System.

K. C. Nicolaou, Mark E. Bunnage, Daniel G. McGarry, Shuhao Shi, Patricia K. Somers, Paul A. Wallace, Xin-Jie Chu, Konstantinos A. Agrios, Janet L. Gunzner, Zhen Yang

Journal:

Year:

1999

File:

PDF, 30 KB

1999

22

Callipeltoside A: Assignment of Absolute and Relative Configuration by Total Synthesis

Barry M. Trost, Olivier Dirat, Janet L. Gunzner

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 78 KB

english, 2002

23

ChemInform Abstract: Total Synthesis of Brevetoxin A. Part 2. Second Generation Strategy and Construction of EFGH Model System.

K. C. Nicolaou, Paul A. Wallace, Shuhao Shi, Michael A. Ouellette, Mark E. Bunnage, Janet L. Gunzner, Konstantinos A. Agrios, Guo-qiang Shi, Peter Gaertner, Zhen Yang

Journal:

Year:

1999

File:

PDF, 28 KB

1999

24

Kupfer(I)-unterstützte Stille-Kupplung von α-stannylsubstituierten Enolethern mit Enoltriflaten: Aufbau von komplexen Polyethergerüsten

Prof. Dr. Kyriacos Costa Nicolaou, Mitsunobu Sato, Neil D. Miller, Janet L. Gunzner, Johanne Renaud, Edouard Untersteller

Journal:

Angewandte Chemie

Year:

1996

File:

PDF, 496 KB

1996

25

ChemInform Abstract: Total Synthesis of Brevetoxin A. Part 4. Final Stages and Completion.

K. C. Nicolaou, Janet L. Gunzner, Guo-qiang Shi, Konstantinos A. Agrios, Peter Gaertner, Zhen Yang

Journal:

Year:

1999

File:

PDF, 26 KB

1999

26

Rational Design of Phosphoinositide 3-Kinase α Inhibitors That Exhibit Selectivity over the Phosphoinositide 3-Kinase β Isoform

Heffron, Timothy P., Wei, BinQing, Olivero, Alan, Staben, Steven T., Tsui, Vickie, Do, Steven, Dotson, Jennafer, Folkes, Adrian J., Goldsmith, Paul, Goldsmith, Richard, Gunzner, Janet, Lesnick, John,

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.42 MB

english, 2011

27

Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity

Wei, Binqing, Gunzner-Toste, Janet, Yao, Hui, Wang, Tao, Wang, Jing, Xu, Zijin, Chen, Jinhua, Wai, John, Nonomiya, Jim, Tsai, Siao Ping, Cruz-Chuh, Josefa dela, Kozak, Katherine Ruth, Liu, Yichin, Yu,

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.77 MB

english, 2017

28

Discovery of Selective LRRK2 Inhibitors Guided by Computational Analysis and Molecular Modeling

Chen, Huifen, Chan, Bryan K., Drummond, Jason, Estrada, Anthony A., Gunzner-Toste, Janet, Liu, Xingrong, Liu, Yichin, Moffat, John, Shore, Daniel, Sweeney, Zachary K., Tran, Thuy, Wang, Shumei, Zhao,

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.16 MB

english, 2012

29

Total Synthesis of Deschlorocallipeltoside A

Trost, Barry M., Gunzner, Janet L.

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 48 KB

english, 2001

30

ChemInform Abstract: Callipeltoside A: Assignment of Absolute and Relative Configuration by Total Synthesis.

Barry M. Trost, Olivier Dirat, Janet L. Gunzner

Journal:

Year:

2002

File:

PDF, 26 KB

2002

31

10.1038/326233b0

Nicolaou, K. C., Yang, Zhen, Shi, Guo-qiang, Gunzner, Janet L., Agrios, Konstantinos A., Gärtner, Peter

Journal:

Year:

1987

File:

PDF, 169 KB

1987

32

Callipeltoside A: Total Synthesis, Assignment of the Absolute and Relative Configuration, and Evaluation of Synthetic Analogues

Trost, Barry M., Gunzner, Janet L., Dirat, Olivier, Rhee, Young H.

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 407 KB

english, 2002

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